Home（https://ahri.gov.et/） » Bacterial and Viral Diseases
Bacterial and Viral Diseases
Bacterial and Viral Diseases Research Directorate (BVDRD) B al Diseases Research
About BVDRD
Publications
Researchers at BVDRD
Graduate Students
Contact
About BVDRD
Background
The Bacterial and Viral Diseases Research Directorate (BVDRD) is one of the research directorates and has two research teams: Bacterial and Fungal Diseases Research and Viral Diseases Research team.
The main research activities of the Directorate is to undertake research activities in the areas mentioned below and contribute in medical research capacity building through supporting Msc and PhD students.
Current research areas:
Understanding aetiology and Molecular Epidemiology of Infectious Diseases
Antimicrobial Resistance
Assessing vaccine efficacy
Development of in-house PCR assays
Training
Publications
2020
Argaw B, Mihret A, Aseffa A, Tarekegne A, Hussen S, Wachamo D, Shimelis T, Howe R. Seroprevalence of hepatitis B virus markers and associated factors among children in Hawassa City, southern Ethiopia. BMC Infect Dis. 2020 Jul 22;20 (1):528.
Teka B, Gizaw M, Ruddies F, Addissie A, Chanyalew Z, Skof AS, Thies S, Mihret A, Kantelhardt EJ, Kaufmann AM, Abebe T. Population-based human papillomavirus infection and genotype distribution among women in rural areas of South Central Ethiopia. Int J Cancer. 2020 Sep 1.
Lemma M, Petkov S, Bekele Y, Petros B, Howe R, Chiodi F. Profiling of Inflammatory Proteins in Plasma of HIV-1-Infected Children Receiving Antiretroviral Therapy. Proteomes. 2020 Sep 7;8(3):E24.
Eshetu D, Shimelis T, Nigussie E, Shumie G, Chali W, Yeshitela B, Assefa A, Gadisa E. Seropositivity to dengue and associated risk factors among non-malarias acute febrile patients in Arba Minch districts, southern Ethiopia. .BMC Infect Dis. 2020 Aug 31;20 (1):639.
Ayana DA, Mulu A, Mihret A, Seyoum B, Aseffa A, Howe R. Occult Hepatitis B virus infection among HIV negative and positive isolated anti-HBc individuals in eastern Ethiopia. Sci Rep. 2020 Dec 17;10(1):22182.
Sebre S, Abegaz WE, Seman A, Awoke T, Desalegn Z, Mihret W, Mihret A, Abebe T Bacterial Profiles and Antimicrobial Susceptibility Pattern of Isolates from Inanimate Hospital Environments at Tikur Anbessa Specialized Teaching Hospital, Addis Ababa, Ethiopia. Infect Drug Resist. 2020 Dec 14;13:4439-4448
Kiros M, Alemayehu DH, Geberekidan E, Mihret A, Maier M, Abegaz WE, Mulu A Increased HIV-1 pretreatment drug resistance with consistent clade homogeneity among ART-naive HIV-1 infected individuals in Ethiopia. Retrovirology. 2020 Sep 29;17(1):33.
Geteneh A, Kassa T, Alemu Y, Alemu D, Kiros M, Andualem H, Abebe W, Alemayehu T, Alemayehu DH, Mihret A, Mulu A, Mihret W. Enhanced identification of Group B streptococcus in infants with suspected meningitis in Ethiopia. PLoS One. 2020 Nov 19;15(11):e0242628
Dessie BK, Melaku S, Gari SR, Ayele BT, Desta AF, Mihret A. Evaluation of toxic elements in nails of tannery workers in Addis Ababa, Ethiopia. Microchemical Journal 2020;159, 105589
2019
Mihret W, Sletbakk Brusletto B, Øvstebø R, Siebke Troseid AM, Norheim G, Merid Y, Kassu A, Abebe W, Ayele S, Silamsaw Asres M, Yamuah L, Aseffa A, Petros B, Caugant DA, Brandtzaeg P Molecular studies of meningococcal and pneumococcal meningitis patients in Ethiopia. Innate Immun. 2019 Apr;25(3):158-167
Abraham Aseffa, Ebba Abate, Berhanu Seyoum, Tesfaye Kassa, Tamrat Abebe, Anteneh Amsalu, Abebaw Bitew, Tsegaye Alemayehu, Zeleke Ayenew, Zeleke Gizachew, Daniel Demissie, Sebsib Neway, Biruk Yeshitela, Andargachew Mulu, Adane Mihret, Taye Tolera Balcha, Rawleigh Howe. Investigations on Antimicrobial Resistance: Contributions of a Clinical Research Network. EMJ 2019 ; Supplement 1: 3
Abebaw Bitew, Birhanemeskel Tegene, Biruk Yeshitila, Rawleigh Howe, Ebba Abate, Mulat Dagnew. Bacterial Profile, Antibacterial Susceptibility Pattern and Associated Factors among Women Attending Antenatal and Postnatal Health Services at the University of Gondar Teaching Hospital, Northwest Ethiopia. EMJ 2019 ; Supplement 1: 9-22
Daniel Demissie, Berhanu Seyoum, Melake Demena, Biruk Yeshitila. Septicemia, Bacterial Isolates and Drug Susceptibility among Women Attending Delivery at Dilchora Hospital, Dire Dawa, Eastern Ethiopia. EMJ 2019 ; Supplement 1: 23
Zeleke Gizachew, Tesfaye Kassa, Getnet Beyene, Rawleigh Howe, Biruk Yeshitela. Multi-Drug Resistant Bacteria and Associated Factors among Reproductive Age Women with Significant Bacteriuria. EMJ 2019 ; Supplement 1: 31
Tsegaye Alemayehu, Endale Tadesse, Sosina Ayalew, Bezaye Nigusse, Biruk Yeshitila, Anteneh Amsalu, Abraham Aseffa. High Burden of Nosocomial Infections Caused by Multi-Drug Resistant Pathogens in Pediatric Patients at Hawassa University Comprehensive Specialized Hospital. EMJ 2019 ; Supplement 1:45
Zeleke Ayenew, Habtamu Biazn, Solomon Gebre-Selassie, Biruk yeshitela, Adane Mihret, Tamrat Abebe. Enteric Pathogens and Antimicrobial Susceptibility Profile among Pediatric Patients with Diarrhea in Addis Ababa, Ethiopia. EMJ 2019 ; Supplement 1: 57
Sebsib Neway, Kassu Desta, Walelign Dessie, Tsehayinesh Lema, Biruk Yeshitila. Bacterial Profile and Antimicrobial Susceptibility Patterns from External Ocular Infections and Associated Risk Factors at the All Africa Leprosy Rehabilitation and Training Center (Alert), Addis Ababa, Ethiopia. EMJ 2019 ; Supplement 1: 67
Rawleigh Howe, Ebba Abate, Berhanu Seyoum, Tesfaye Kassa, Tamrat Abebe, Seifegebriel Teshome, Habtamu Biazin, Getnet Ayalew, Mekuanint Geta, Rebie Kedir, Belayneh Dimah, Fitsum Abebe, Seifudin Usman, , Andargachew Mulu, Adane Mihret, Taye Tolera Balcha, Abraham Aseffa. Exploring the Impact of Childhood HBV Vaccination in Ethiopia: A Synopsis and Discussion of Preliminary Findings. EMJ 2019 ; Supplement 2: 87
Mekuanint Geta, Getnet Ayalew, Endalew Yizengaw, Adane Mihret, Abraham Aseffa, Rowliegh Howe, Feleke Moges, Ebba Abate. Seroprevalence of Hepatitis B Virus Infection and Associated Factors Among Mothers In Gondar, North-West Ethiopia: A Population Based Study. EMJ 2019 ; Supplement 1: 97
Belayne Dimah Taye, Tesfaye Kassa, Lule Teshager, Rebie Kedir Addisu Gize Yeshanew, Abraham Aseffa, Rawleigh Howe, Adane Mihret. Prevalence and Associated Risk Factors of Hepatitis B and C Virus Infections among Mothers in Jimma, South West Ethiopia: A Community-Based Study. EMJ 2019 ; Supplement 2: 109
Fitsum Abebe, Berhanu Seyoum, Zelalem Teklemariam, Lemessa Oljira, Azeb Tarekegne, Fiker Bekele, Adane Mihret, Abraham Aseffa, Rawleigh Howe. Seroprevalence of Hepatitis B Virus Surface Antigen, Anti-Hepatitis C Virus Antibody and their Associated Factors among Mothers Living in Harar, Eastern Ethiopia. EMJ 2019 ; Supplement 2: 119
Habtamu Biazin, Seifegebriel Teshome, Zeleke Ayenew, Tamratabebe, Adane Mihret, Abraham Aseffa, Rawleigh Howe. Determining Seroprevalence of Hepatitis B And C Virus Infections And Associated Risk Factors Among Apparently Healthy Mothers In Addis Ababa, Ethiopia. EMJ 2019 ; Supplement 2: 129
Getnet Ayalew, Abate Assefa, Antenehamsalu, Mekuanint Geta, Adane Mihret, Abraham Aseffa, Rawleigh Howe, Ebba Abate. Immune Protection of Hepatitis B Vaccine among Children Living in Gondar, Northwest Ethiopia. EMJ 2019 ; Supplement 2: 139
Rebie Kedir, Belayneh Dimah Taye, Tesfaye Kassa, Lule Teshager, Abraham Aseffa, Rawleigh Howe, Adane Mihiret, Addisu Gezie Seroprevalence o f Hepatitis B Virus Infection And Seroprotection Of Hepatitis B Vaccine Among Children In Jimma Town, Southwest Ethiopia. EMJ 2019 ; Supplement 2: 147
Seifudin Usman, Berhanu Seyoum, Bezatu Mengiste, Azeb Tarekegne, Fiker Bekele, Adane Mihret, Abraham Aseffa, Rawleigh Howe. Serum Level of Anti-Hepatitis B Surface Antigen and Hbv Associated Factors among Vaccinated and Unvaccinated Children in Harar, Eastern Ethiopia: A Community-Based Study. EMJ 2019 ; Supplement 2: 159
Seifegebriel Teshome, Habtamu Biazin, Azeb Tarekegne, Tamrat Abebe, Fiker Bekele, Adane Mihret, Abraham Aseffa, Rawleigh Howe.Antibody Response against Hepatitis B Virus after Vaccination and Seroprevalence of Hbv in Children in Addis Ababa, Ethiopia. EMJ 2019 ; Supplement 2: 167
Bodin J, Mihret A, Holm-Hansen C, Dembinski JL, Trieu MC, Tessema B, Tarekegne A, Yimer SA, Cox R, Aseffa A, Haneberg B, Mjaaland S. Vitamin D Deficiency is Associated with Increased Use of Antimicrobials among Preschool Girls in Ethiopia. Nutrients. 2019 7;11(3)
Toy T, Pak GD, Duc TP, Campbell JI, El Tayeb MA, Von Kalckreuth V, Im J, Panzner U, Cruz Espinoza LM, Eibach D, Dekker DM, Park SE, Jeon HJ, Konings F, Mogeni OD, Cosmas L, Bjerregaard-Andersen M, Gasmelseed N, Hertz JT, Jaeger A, Krumkamp R, Ley B, Thriemer K, Kabore LP, Niang A, Raminosoa TM, Sampo E, Sarpong N, Soura A, Owusu-Dabo E, Teferi M, Yeshitela B, Poppert S, May J, Kim JH, Chon Y, Park JK, Aseffa A, Breiman RF, Schütt-Gerowitt H, Aaby P, Adu-Sarkodie Y, Crump JA, Rakotozandrindrainy R, Meyer CG, Sow AG, Clemens JD, Wierzba TF, Baker S, Marks F. Multicountry Distribution and Characterization of Extended-spectrum β-Lactamase-associated Gram-negative Bacteria From Bloodstream Infections in Sub-Saharan Africa. Clin Infect Dis. 2019 Oct 30;69(Suppl 6):S449-S458
Leon ME, Kassa E, Bane A, Gemechu T, Tilahun Y, Endalafer N, McKay-Chopin S, Brancaccio RN, Ferro G, Assefa M, Ward E, Tommasino M, Aseffa A, Schüz J, Jemal A, Gheit T. Prevalence of human papillomavirus and Helicobacter pylori in esophageal and gastroesophageal junction cancer biopsies from a case-control study in Ethiopia. Infect Agent Cancer. 2019 Aug 7;14:19
Mogeni OD, Cruz Espinoza LM, Im J, Panzner U, Toy T, Pak GD, Haselbeck A, Ramani E, Schütt-Gerowitt H, Jacobs J, Metila OL, Adewusi OJ, Okeke IN, Ogunleye VI, Owusu-Dabo E, Rakotozandrindrainy R, Soura AB, Teferi M, Roy KC, Macwright W, Breiman RF, Kim JH, Mogasale V, Baker S, Park SE, Marks F. The Monitoring and Evaluation of a Multicountry Surveillance Study, the Severe Typhoid Fever in Africa Program. Clin Infect Dis. 2019 Oct 30;69(Suppl 6):S510-S518
Park SE, Toy T, Cruz Espinoza LM, Panzner U, Mogeni OD, Im J, Poudyal N, Pak GD, Seo H, Chon Y, Schütt-Gerowitt H, Mogasale V, Ramani E, Dey A, Park JY, Kim JH, Seo HJ, Jeon HJ, Haselbeck A, Conway Roy K, MacWright W, Adu-Sarkodie Y, Owusu-Dabo E, Osei I, Owusu M, Rakotozandrindrainy R, Soura AB, Kabore LP, Teferi M, Okeke IN, Kehinde A, Popoola O, Jacobs J, Lunguya Metila O, Meyer CG, Crump JA, Elias S, Maclennan CA, Parry CM, Baker S, Mintz ED, Breiman RF, Clemens JD, Marks F. The Severe Typhoid Fever in Africa Program: Study Design and Methodology to Assess Disease Severity, Host Immunity, and Carriage Associated With Invasive Salmonellosis. Clin Infect Dis. 2019 Oct 30;69(Suppl 6):S422-S434.
2018
Adal M, Howe R, Kassa D, Aseffa A, Petros B. Associations of gender and serum total cholesterol with CD4+ T cell count and HIV RNA load in antiretroviral-naïve individuals in Addis Ababa.BMC Public Health. 2018 Jul 31;18(1):943
Adal M, Howe R, Kassa D, Aseffa A, Petros B. Malnutrition and lipid abnormalities in antiretroviral naïve HIV-infected adults in Addis Ababa: A cross-sectional study. PLoS One. 2018 Apr 19;13(4):e0195942
Park SE, Pham DT, Boinett C, Wong VK, Pak GD, Panzner U, Espinoza LMC, von Kalckreuth V, Im J, Schütt-Gerowitt H, Crump JA, Breiman RF, Adu-Sarkodie Y, Owusu-Dabo E, Rakotozandrindrainy R, Soura AB, Aseffa A, Gasmelseed N, Keddy KH, May J, Sow AG, Aaby P, Biggs HM, Hertz JT, Montgomery JM, Cosmas L, Olack B, Fields B, Sarpong N, Razafindrabe TJL, Raminosoa TM, Kabore LP, Sampo E, Teferi M, Yeshitela B, et al, Marks F, Baker S. The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa. Nat Commun . 2018 Nov 30;9(1):5094.
Bitew Kifilie A, Dagnew M, Tegenie B, Yeshitela B, Howe R, Abate E.Bacterial Profile, Antibacterial Resistance Pattern, and Associated Factors from Women Attending Postnatal Health Service at University of Gondar Teaching Hospital, Northwest Ethiopia. Int J Microbiol . 2018 Feb 25;2018: 3165391.
Huruy K, Mulu A, Liebert UG, Maier M. Correction: HIV-1C proviral DNA for detection of drug resistance mutations. PLoS One. 2018 Nov 1;13(11):
Belyhun Y, Moges F, Endris M, Asmare B, Amare B, Bekele D, Tesfaye S, Alemayehu M, Biadgelegne F, Mulu A, Assefa Y. Ocular bacterial infections and antibiotic resistance patterns in patients attending Gondar Teaching Hospital, Northwest Ethiopia.BMC Res Notes. 2018 Aug 17;11(1):597
Baron U, Werner J, Schildknecht K, Schulze JJ, Mulu A, Liebert UG, Sack U, Speckmann C, Gossen M, Wong RJ, Stevenson DK, Babel N, Schürmann D, Baldinger T, Bacchetta R, Grützkau A, Borte S, Olek S. Epigenetic immune cell counting in human blood samples for immunodiagnostics. SciTransl Med. 2018 Aug 1;10(452).
Ferede G, Tiruneh M, Abate E, Wondimeneh Y, Damtie D, Gadisa E, Howe R, Aseffa A, Tessema BA serologic study of dengue in northwest Ethiopia: Suggesting preventive and control measures. PLoSNegl Trop Dis . 2018 May 31;12(5):e0006430.
Greenwood BM, Aseffa A, Caugant DA, Diallo K, Kristiansen PA, Maiden MCJ, Stuart JM, Trotter CL. Narrative review of methods and findings of recent studies on the carriage of meningococci and other Neisseria species in the African Meningitis Belt .Trop Med Int Health. 2018 Nov 21
Ferede G, Tiruneh M, Abate E, Wondimeneh Y, Gadisa E, Howe R, Aseffa A, Tessema B. A study of clinical, hematological, and biochemical profiles of patients with dengue viral infections in Northwest Ethiopia: implications for patient management. BMC Infect Dis. 2018 Dec 4;18(1):616.
Steinmetz I, Wagner GE, Kanyala E, Sawadogo M, Soumeya H, Teferi M, Andargie E, Yeshitela B, YabaAtsé-Achi L, Sanogo M, Bonfoh B, Rakotozandrindrainy R, PongomboShongo C, Shongoya Pongombo M, KasambaIlunga E, Lichtenegger S, Assig K, May J, Bertherat E, Owusu M, Owusu-Dabo E, Adu-Sarkodie Y.