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Traditional and Modern Medicine Research and Development Directorate

Traditional and Modern Medicine Research and Development Directorate (TMMRDD)

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About TMMRDD

Plants have been used as a source of medicine in Ethiopia from time immemorial to treat different ailments. This is often linked to ethnic and cultural diversity coupled with an array of unique flora and fauna that are employed as the prime-tools in the fight against numerous health problems. Even with the advent of modern medicine, this indigenous health care delivery system is the major source of care for an estimated 80% of the population. More than 95% of traditional medical preparations are of plant origin The Ethiopian flora is estimated to contain between 6500 and 7000 species of higher plants of which about 12% are endemic. The Directorate of Traditional and Modern Medicine Research and Development (TMMRDD) within AHRI conducting operational and basic research on the quality, efficacy and safety of traditional and modern medicine including the factors affecting the rational utilization and factors determine drug resiststance for the major health problems of the country.

Strategic Themes of the Directorate

Enhance innovation and production of standardized plant based medicine products,

Generate evidence based research on traditional and modern medicine

Raise awareness of the community through appropriate mechanisms

Strategic results

Validated traditional medicine production packages for public use ;

Evidence on safety, efficacy and quality of traditional and Modern medicine for policy and programs implementers;

Community awareness, guidelines, manuals, pharmacopoeias and data base;

The directorate has four divisions

Traditional Medicine and Nutraceuticals Research and Development Division (TMNRDD)

Safety and Efficacy research and development Division

Medicine Formulation and Quality control Research and Development Division

Modern Medicine and In Silico Research and Development Division, MMIRDD

Traditional Medicine and Nutraceuticals Research and Development Division (TMNRDD) The Traditional Medicine and Nutraceuticals Research and Development Division focuses on the phytochemical analysis of natural products, identify active ingredients, characterization and structural elucidations of herbal medicines, protocol development on quality analysis of herbal medicines and nutraceuticals, for commonly utilized traditional medicines and priority public health problems of the country. Major activities of Traditional Medicine and Nutraceuticals Research and Development Division. Collect, scientifically identify and authenticate medicinal plants selected for various laboratory investigation.

Preparation of crude extracts and other fractions for bioassays.

Chemical screening of plants, animals, mineral substances and nutraceuticals used in traditional medicine.

Bioassay guided separation of active substances of plant, mineral or animal origin used in traditional medicine.

Characterize and identify of biologically active ingredient for potentially candidate medicinal plants and nutraceuticals.

Structure elucidation of biologically active isolated compounds.

Conduct Structural elucidation of bioactive natural products.

Establish thematic botanical gardens for conservation of medicinal and endangered plants.

Establish national medicinal plant herbarium for preservation of medicinal plants

develop products of standardized and validated herbal medicine and other source of natural products for Clinical Trials

provide consultancy services to public and industrial sectors

Develop quality control protocol for marketed traditional medicines

Conduct survey on Traditional Medicines and Traditional Medicine Practice

Liaises with the statutory bodies for the regulation and control of Traditional Medicine products and practices and to provide support in the performance of their functions

Develop personnel with high expertise in phytomedicine and nutraceuticals

Medicine Formulation and Quality control Research and Development Division The division focuses on the development of production packages from validated herbal medicines for the treatment of major public health problems of the country. The division studies the appropriate dosage form design, quality and specifications of herbal preparations, standardization of herbal products and determines the stability of the herbal products in the country. Major activities of the Division;

Carry out studies on value-added safe and standardized herbal products, nutraceuticals and other source of natural products.

Study methods of production of traditional medicines of proven therapeutic efficacy,