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The 5xmille donation
Support scientific research, donate your 5xmille to SISSA
This year too, it is possible to allocate the 5x1000 share of the personal income tax (Irpef) to universities and research centers. You can therefore personally and concretely contribute to the support of Italian scientific research, an important resource for our future and for the development of the country.
Donate your 5xmille to SISSA - tax code 80035060328
How to donate:
To donate your 5xmille to SISSA, just indicate it to your accountant or CAF when filling out your tax return and enter the tax code 80035060328 in the box "Financing of scientific research and universities" and sign in the space below in the 730 form, Unico form or the specific box of the CU form.
If your signature is not accompanied by the tax code, your 5xmille will be divided proportionally to the number of preferences received by the organizations belonging to the same box, in this case that of scientific research and universities.
The choice to allocate the 5xmille to research is not an alternative to financing religious cults (law no. 222 of 1985). Those who decide to support us can therefore allocate the 8 per mille contribution to a confessional entity.
Financed projects:
Audrey Francesca Biagioni
Studying innovative drug delivery for epilepsy
What research has your group conducted thanks to the donations from the 5xmille? Thanks to the support of the 5x1000 donations, our research group has been able to advance the development of a new therapeutic platform for the treatment of epilepsy, based on advanced carbon nanomaterials and innovative pharmaceutical formulations.
Our research focuses on the development of an innovative smart microdevice for controlled drug delivery. The technology employs graphene oxide nanosheets that enable rapid, precise, and programmable release of anti-epileptic therapy.This technology is already protected by an international patent owned by SISSA, representing an important achievement in the valorization of scientific research developed within the institute. The goal is to provide an innovative solution for epileptic emergencies, enabling timely intervention that can improve patients’ safety, autonomy, and quality of life.
Thanks to the 5x1000 donations, it has been possible to support the experimental development of the technology, the preliminary validation of the electrochemical system, and the study of the controlled drug-release dynamics. This has allowed us to develop new pharmaceutical parameters aimed at improving the speed of action and the overall effectiveness of the therapy, leading to better control of epileptic symptoms.
The donations have also contributed to preparing the next studies needed to bring this research closer to future clinical application.
Why do you believe it is important to donate these funds to SISSA and what invitation would you extend to people to donate their 5xmille to SISSA? Supporting SISSA means investing in research capable of transforming scientific discovery into a real improvement in people’s lives. Science is not only knowledge: it is innovation, change, and a concrete opportunity to develop new therapies and technologies for patients. Thanks to the 5x1000, we can continue advancing the development of innovative solutions, such as new therapeutic platforms for the treatment of epilepsy, and bring research ever closer to patients.
Every contribution helps researchers and research groups transform innovative ideas into real solutions with a tangible impact on health and the future of medicine.
2025 Project: SINDREL - Precision Therapeutics
Eugenio Piasini
Studying neurons computationally
What research has your group conducted thanks to the donations from the 5xmille? My research group focuses on computational neuroscience, and one of our current themes is the development of statistical methods for analyzing experimental data that allow us to rigorously answer questions like those just mentioned. 5 × 1000 funds help support our work in this area, enabling us above all to acquire the computational resources needed to iterate rapidly on our model designs. The research is still in an early stage, but thanks also to valuable collaborations with various experimental groups in Italy and abroad, we already have our first encouraging results, which we hope to publish in the coming years. Why do you believe it is important to donate these funds to SISSA and what invitation would you extend to people to donate their 5xmille to SISSA? The 5xmille has been a fundamental support in allowing my newly formed group to advance this project. I believe it is very important for each of us, in our own small way, to contribute to the progress of biomedical scientific research with a small gesture, such as donating our 5xMille. Indeed, the choices we make today will bear fruit in the medical and health advancements we will see in the coming years, which will bring improvements for everyone. Choosing to donate it to SISSA means supporting high-quality scientific research projects, carried out by qualified scientists who are passionate about their work, in a top-level environment.
2024 Project: Heterogeneous neural coding
Alessia Soldano
Studying Alzheimer's Disease
What research has your group conducted thanks to the donations from the 5xmille? Thanks to the support of the 5xmille, my group has developed a project aimed at studying the role of brain inflammation in Alzheimer's Disease. This neurodegenerative disease is the most common form of dementia in the elderly and remains incurable to this day. Recent years have seen the emergence of neuro-inflammation as a factor in the onset and progression of Alzheimer's, but there is still much work to be done to fully understand these mechanisms and translate them into treatments. Our project hypothesizes that an increase in neuro-inflammation may represent a crucial and initial step in this disease, and that addressing this process early on may delay or alleviate the onset of symptoms. In the laboratory, we use the fruit fly, Drosophila melanogaster, as a model to study these processes. Thanks to our "Alzheimer's flies," we can monitor the onset of specific symptoms while simultaneously assessing brain inflammation. The project is still in its early stages but is already yielding its first interesting results, and we hope, within a couple of years, to have a precise understanding of the timing of inflammation onset and its effects on neurodegeneration. Why do you believe it is important to donate these funds to SISSA and what invitation would you extend to people to donate their 5xmille to SISSA? The 5xmille has been a fundamental support in allowing my newly formed group to advance this project. I believe it is very important for each of us, in our own small way, to contribute to the progress of biomedical scientific research with a small gesture, such as donating our 5xMille. Indeed, the choices we make today will bear fruit in the medical and health advancements we will see in the coming years, which will bring improvements for everyone. Choosing to donate it to SISSA means supporting high-quality scientific research projects, carried out by qualified scientists who are passionate about their work, in a top-level environment.
2023 Project: Study of the role of brain inflammation in the pathogenesis of Alzheimer's disease
Remo Sanges
Studying Xia-Gibbs Syndrome
What research has your group done thanks to the donations of the 5xmille?